BEAUTIFY TIME
Redefine collagen peptides with Definisse [KP¹]® Collagen Modulator Bio-Peptide - our best-in-class formula designed to protect and enhance your skin.
You can’t stop time, but you can slow it down and make it beautiful. Introducing our pioneering Definisse [KP1]® Collagen Modulator Bio-Peptide, the answer to your complete collagen protection.
Our natural collagen is essential for maintaining healthy, younger-looking skin. However, as we age, our skin’s ability to replenish our natural collagen reduces every year by 1 - 1.5%.1
Traditional treatments attempt to stimulate collagen production; imagine trying to fill a bucket with a hole in the bottom, it’s a strategy that doesn’t work long-term. Our Definisse [KP1]® range takes a different approach.
Our exclusive key ingredient, Key Peptide 1 [KP1]®, works to protect your collagen from degradation,2-5 preserving your natural collagen for radiant, younger-looking skin.
Start your skincare journey by finding a clinic near you to access the complete at-home skincare range
DISCOVER OUR COMPLETE DEFINISSE [KP1]® RANGE
Definisse [KP¹]® Key Peptide 1 is a collagen modulator with a bio-active agent that works to inhibit the functioning of the enzymes responsible for depleting collagen.
It helps to increase your collagen levels by protecting what you naturally produce and may even stimulate production when used in conjunction with minimally invasive aesthetic treatments.
By protecting collagen, Definisse [KP¹]® Collagen Modulator Bio-Peptide has been clinically proven to increase Collagen Type 1 density in the structural fibres of human skin.12
The Definisse [KP¹]® Collagen Modulator Bio-Peptide range of creams and serum can reduce all the signs of ageing associated with collagen depletion.
Clinically proven to reduce wrinkles and fine lines, smooth and brighten skin, increase skin density and firmness.
Definisse [KP¹]® Collagen Modulator Bio-Peptide is an at-home skincare range of luxurious products that are simply massaged into your skin as part of your daily routine.
Apply a few drops to clean skin in the morning and evening by massaging until completely absorbed. Can be used in combination with aesthetic medicine treatments such as fillers and threads to improve results.
This first in class innovation, Definisse [KP¹]® Collagen Modulator Bio-Peptide, is a skin care range that contains both high and low molecular weight Hyaluronic Acid (HA) and the exclusive key peptide 1 bio-active peptide derived from the Serine Protease Inhibitor Serpin A1. It is the Serpin A1 peptide that inhibits the degradation of collagen.13
Our skin care line also contains skin stimulating vitamins, antioxidants and moisturisers, therefore, not only protecting collagen, but increasing hydration and skin regeneration in one amazing luxurious and pleasurable skin care treatment.
And if all of this sounds too good to be true - Definisse [KP¹]® Collagen Modulator Bio-Peptide has been clinically proven to decrease wrinkles by 10% and increase hydration by 30% in just 4 weeks.13
Pro-aging Skincare
Take control of your skin with this unique and exclusive collagen preservation skincare programme.
Clinically proven, in collaboration with the University of Florence, as effective in achieving significant improvement on five anti-aging parameters after only 4 weeks of use: hydration, elasticity, density, roughness, and brightness.
This is made possible through the bio-active functions of the product, which are proven to increase skin density through an increase, or reorganisation, of the dermal structures: collagen fibres, cells and extracellular matrix.16
Unprecedented results from an unprecedented innovation.
References
- Reilly DM, Lozano J, Uitto J. Skin collagen through the lifestages: importance for skin health and beauty. Plast Aesthet Res. 2021;8:2.
- Cipriani C, Teti G, Ratta M, Santarelli A, Nannicini C, Ruggeri A, et al. Serpin A1 and the modulation of type I collagen turnover: Effect of the C-terminal peptide 409–418 (SA1-III) in human dermal fibroblasts. Cell Biol Int. 2018;9999:1-9.
- Errante F, Toccafondi N, Petrone L, Rovero P. Cosmeceutical peptides in the framework of sustainable wellness economy. Front Chem. 2020;8:572923.
- Pascarella S, Errante F, Rovero P. Serpin A1 C-terminal peptides as collagen turnover modulators. ChemMedChem. 2016;11:1850-5.
- Rovero P, Toccafondi N, Nannicini C, Petrone L, Errante F. The clinical evidence-based paradigm of topical anti-aging skincare formulations enriched with bio-active peptide SA1-III (KP1) as collagen modulator: from bench to bedside. Clin Cosmet Investig Dermatol. 2022;15:2693-703.